Product Browser

Last updated: 2017/7/16

Product Compare

Product Compare Cancel Click this icon to add products to compare list. Select up to 10 products.

Quick Order (Tutorial)

Input Catalog #,
place order here!
Catalog # :
  • Where to buy
  • Choose your location

NFASC polyclonal antibody

  • Catalog # : PAB19682
  • Visit Frequency :
  • Countries :
  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of NFASC.
  • Immunogen:
  • A synthetic peptide corresponding to amino acids 877-890 at internal region of human NFASC.
  • Sequence:
  • C-NFSPNQTKFTVQRT
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 138
  • Reactivity:
  • Human, Rat
  • Specificity:
  • This antibody is expected to recognize reported isoforms 1, 2, 3 and 4 (NP_001005388.2;,NP_001153803.1, NP_001153804.1and NP_055905.2 resp).
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Recommend Usage:
  • Western Blot (0.5-2 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • NFASC polyclonal antibody (Cat # PAB19682) (0.5 ug/mL) staining of human lung lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • ELISA
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Protein Accession#:
  • NP_001005388.2;NP_001153803.1;NP_001153804.1;NP_055905.2
  • Gene Name:
  • NFASC
  • Gene Alias:
  • DKFZp686P2250,FLJ46866,KIAA0756,NF,NRCAML
  • Gene Description:
  • neurofascin homolog (chicken)
  • Gene Summary:
  • This gene encodes an L1 family immunoglobulin cell adhesion molecule with multiple IGcam and fibronectin domains. The protein functions in neurite outgrowth, neurite fasciculation, and organization of the axon initial segment (AIS) and nodes of Ranvier on axons during early development. Both the AIS and nodes of Ranvier contain high densities of voltage-gated Na+ (Nav) channels which are clustered by interactions with cytoskeletal and scaffolding proteins including this protein, gliomedin, ankyrin 3 (ankyrin-G), and betaIV spectrin. This protein links the AIS extracellular matrix to the intracellular cytoskeleton. This gene undergoes extensive alternative splicing, and the full-length nature of some variants has not been determined
  • Other Designations:
  • OTTHUMP00000065305,OTTHUMP00000065306,OTTHUMP00000065307,OTTHUMP00000065308,OTTHUMP00000065313,OTTHUMP00000065315,OTTHUMP00000065321,OTTHUMP00000065322,OTTHUMP00000065324,neurofascin
  • Related Disease
  • RSS
  • YouTube
  • Linkedin
  • Facebook