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IDS polyclonal antibody

  • Catalog # : PAB19674
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of IDS.
  • Immunogen:
  • A synthetic peptide corresponding to internal region of human IDS.
  • Sequence:
  • C-KHFRFRDLEEDP
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 61.9
  • Reactivity:
  • Human
  • Specificity:
  • This antibody is expected to recognize isoform a (NP_000193.1).
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 0.5 mg/mL
  • Recommend Usage:
  • ELISA (1:16000)
    Western Blot (0.1-0.3 ug/mL)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (3-5 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 0.5 mg/mL Tris saline, pH 7.3 (0.02% sodium azide, 0.5% BSA)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • IDS polyclonal antibody (Cat # PAB19674) (0.1 ug/mL) staining of human liver lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • IDS polyclonal antibody (Cat # PAB19674) (3.8 ug/mL) staining of paraffin embedded human placenta. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
  • ELISA
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 3423
  • Gene Name:
  • IDS
  • Gene Alias:
  • MPS2,SIDS
  • Gene Description:
  • iduronate 2-sulfatase
  • Gene Summary:
  • Iduronate-2-sulfatase is required for the lysosomal degradation of heparan sulfate and dermatan sulfate. Mutations in this X-chromosome gene that result in enzymatic deficiency lead to the sex-linked Mucopolysaccharidosis Type II, also known as Hunter Syndrome. Iduronate-2-sulfatase has a strong sequence homology with human arylsulfatases A, B, and C, and human glucosamine-6-sulfatase. A splice variant of this gene has been described. [provided by RefSeq
  • Other Designations:
  • Hunter syndrome,OTTHUMP00000024207,OTTHUMP00000024210,alpha-L-iduronate sulfate sulfatase,iduronate-2-sulfatase,idursulfase
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