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Last updated: 2017/3/26

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GM2A polyclonal antibody

  • Catalog # : PAB19671
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of GM2A.
  • Immunogen:
  • A synthetic peptide corresponding to amino acids 164-175 at internal region of human GM2A.
  • Sequence:
  • C-TTGNYRIESVLS
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 28
  • Reactivity:
  • Human
  • Specificity:
  • This antibody is expected to recognize isoform 1 (NP_000396.2) only.
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Recommend Usage:
  • ELISA (1:4000)
    Western Blot (1-2 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • HEK293 lysate (10 ug protein in RIPA buffer) overexpressing human GM2A with DYKDDDDK tag probed with GM2A polyclonal antibody (Cat # PAB19671) (1.0 ug/mL) in lane 1 and probed with anti- DYKDDDDK Tag (1/30000) in lane 3. Mock-transfected HEK293 probed with GM2A polyclonal antibody (Cat # PAB19671) (1 mg/mL) in lane 2. Primary incubations were for 1 hour. Detected by chemiluminescence.
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 2760
  • Gene Name:
  • GM2A
  • Gene Alias:
  • SAP-3
  • Gene Description:
  • GM2 ganglioside activator
  • Gene Summary:
  • This gene encodes a small glycolipid transport protein which acts as a substrate specific co-factor for the lysosomal enzyme beta-hexosaminidase A. Beta-hexosaminidase A, together with GM2 ganglioside activator, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Mutations in this gene result in GM2-gangliosidosis type AB or the AB variant of Tay-Sachs disease. [provided by RefSeq
  • Other Designations:
  • cerebroside sulfate activator protein,sphingolipid activator protein 3
  • Gene Pathway
  • Related Disease
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