PKP2 polyclonal antibody
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More Files
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Western Blot (Tissue lysate)
PKP2 polyclonal antibody (Cat # PAB19653) (0.3 ug/mL) staining of mouse heart lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of PKP2.
Immunogen
A synthetic peptide corresponding to amino acids 125-139 at internal region of human PKP2.
Sequence
C-RGTAQYSSQKSVEER
Host
Goat
Theoretical MW (kDa)
88.1, 87.8
Reactivity
Mouse, Rat
Specificity
This antibody is expected to recognize both reported isoforms (NP_001005242.2; NP_004563.2).
Form
Liquid
Purification
Antigen affinity purification
Recommend Usage
ELISA (1:16000)
Western Blot (0.3-1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
PKP2 polyclonal antibody (Cat # PAB19653) (0.3 ug/mL) staining of mouse heart lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — PKP2
Entrez GeneID
5318Protein Accession#
NP_001005242.2;NP_004563.2Gene Name
PKP2
Gene Alias
ARVD9, MGC177501
Gene Description
plakophilin 2
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This gene product may regulate the signaling activity of beta-catenin. Two alternately spliced transcripts encoding two protein isoforms have been identified. A processed pseudogene with high similarity to this locus has been mapped to chromosome 12p13. [provided by RefSeq
Other Designations
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Interactome
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Pathway
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Disease
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