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Last updated: 2017/7/23

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KCNQ1 polyclonal antibody

  • Catalog # : PAB19652
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of KCNQ1.
  • Immunogen:
  • A synthetic peptide corresponding to C-terminus of human KCNQ1.
  • Sequence:
  • C-EQLTVPRRGPDEGS
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 61.5, 28
  • Reactivity:
  • Human
  • Specificity:
  • This antibody is expected to recognize both reported isoforms (NP_000209.2; NP_861463.1).
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Recommend Usage:
  • ELISA (1:16000)
    Western Blot (1-3 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • KCNQ1 polyclonal antibody (Cat # PAB19652) (1 ug/mL) staining of human heart lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • ELISA
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 3784
  • Protein Accession#:
  • NP_000209.2;NP_861463.1
  • Gene Name:
  • KCNQ1
  • Gene Alias:
  • ATFB1,FLJ26167,JLNS1,KCNA8,KCNA9,KVLQT1,Kv1.9,Kv7.1,LQT,LQT1,RWS,SQT2,WRS
  • Gene Description:
  • potassium voltage-gated channel, KQT-like subfamily, member 1
  • Gene Summary:
  • This gene encodes a protein for a voltage-gated potassium channel required for the repolarization phase of the cardiac action potential. The gene product can form heteromultimers with two other potassium channel proteins, KCNE1 and KCNE3. Mutations in this gene are associated with hereditary long QT syndrome, Romano-Ward syndrome, Jervell and Lange-Nielsen syndrome and familial atrial fibrillation. The gene is located in a region of chromosome 11 that contains a large number of contiguous genes that are abnormally imprinted in cancer and the Beckwith-Wiedemann syndrome. Two alternative transcripts encoding distinct isoforms have been described. [provided by RefSeq
  • Other Designations:
  • Jervell and Lange-Nielsen syndrome 1,kidney and cardiac voltage dependend K+ channel,long (electrocardiographic) QT syndrome, Ward-Romano syndrome 1,slow delayed rectifier channel subunit
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