Product Browser

Last updated: 2016/12/4

Product Compare

Product Compare Cancel Click this icon to add products to compare list. Select up to 10 products.

Quick Order (Tutorial)

Input Catalog #,
place order here!
Catalog # :
  • Where to buy
  • Choose your location

DCX polyclonal antibody

  • Catalog # : PAB19645
  • Visit Frequency :
  • Countries :
  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of DCX.
  • Immunogen:
  • A synthetic peptide corresponding to amino acids 232-242 at internal region of human DCX.
  • Sequence:
  • C-KTSANMKAPQS
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 49.3, 40.6
  • Reactivity:
  • Mouse
  • Specificity:
  • This antibody is expected to recognize all four reported isoforms (NP_000546.2; NP_835365.1; NP_835364.1; NP_001182482.1). Reported variants represent identical protein: NP_835364.1 and NP_835366.1.
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Recommend Usage:
  • ELISA (1:32000)
    Western Blot (0.01-0.03 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • DCX polyclonal antibody (Cat # PAB19645) (0.01 ug/mL) staining of mouse fetal brain lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • ELISA
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 1641
  • Protein Accession#:
  • NP_000546.2;NP_835365.1;NP_835364.1;NP_001182482.1
  • Gene Name:
  • DCX
  • Gene Alias:
  • DBCN,DC,LISX,SCLH,XLIS
  • Gene Description:
  • doublecortin
  • Gene Summary:
  • In the developing cortex, cortical neurons must migrate over long distances to reach the site of their final differentiation. The protein encoded by this gene is a cytoplasmic protein which appears to direct neuronal migration by regulating the organization and stability of microtubules. The encoded protein contains two doublecortin domains, which bind microtubules. In addition, the encoded protein interacts with LIS1, the regulatory gamma subunit of platelet activating factor acetylhydrolase, and this interaction is important to proper microtubule function in the developing cortex. Mutations in this gene are a cause of X-linked lissencephaly. Multiple transcript variants encoding at least three different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000062892,doublecortex,doublin,lissencephalin-X
  • RSS
  • YouTube
  • Linkedin
  • Facebook