Product Browser

Last updated: 2016/12/4

Product Compare

Product Compare Cancel Click this icon to add products to compare list. Select up to 10 products.

Quick Order (Tutorial)

Input Catalog #,
place order here!
Catalog # :
  • Where to buy
  • Choose your location

CHRNA4 polyclonal antibody

  • Catalog # : PAB19643
  • Visit Frequency :
  • Countries :
  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of CHRNA4.
  • Immunogen:
  • A synthetic peptide corresponding to internal region of human CHRNA4.
  • Sequence:
  • C-HVETRAHAEERLLKK
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 70, 70.2
  • Reactivity:
  • Human, Rat
  • Specificity:
  • This antibody is expected NOT to cross-react with the similar alpha 2 subunit.
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 0.5 mg/mL
  • Recommend Usage:
  • ELISA (1:64000)
    Western Blot (1-3 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • CHRNA4 polyclonal antibody (Cat # PAB19643) (0.3 ug/mL) staining of rat brain lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • ELISA
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 1137
  • Gene Name:
  • CHRNA4
  • Gene Alias:
  • BFNC,EBN,EBN1,FLJ95812,NACHR,NACHRA4,NACRA4
  • Gene Description:
  • cholinergic receptor, nicotinic, alpha 4
  • Gene Summary:
  • This gene encodes a nicotinic acetylcholine receptor, which belongs to a superfamily of ligand-gated ion channels that play a role in fast signal transmission at synapses. These pentameric receptors can bind acetylcholine, which causes an extensive change in conformation that leads to the opening of an ion-conducting channel across the plasma membrane. This protein is an integral membrane receptor subunit that can interact with either nAChR beta-2 or nAChR beta-4 to form a functional receptor. Mutations in this gene cause nocturnal frontal lobe epilepsy type 1. Polymorphisms in this gene that provide protection against nicotine addiction have been described. [provided by RefSeq
  • Other Designations:
  • cholinergic receptor, nicotinic, alpha 4 subunit,cholinergic receptor, nicotinic, alpha polypeptide 4,neuronal nicotinic acetylcholine receptor alpha-4 subunit
  • RSS
  • YouTube
  • Linkedin
  • Facebook