RGS13 polyclonal antibody
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More Files
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of RGS13.
Immunogen
A synthetic peptide corresponding to N-terminus of human RGS13.
Sequence
DESKRPPSNLTLEE-C
Host
Goat
Theoretical MW (kDa)
19.1
Reactivity
Human
Specificity
Reported variants represent identical proteins: NP_002918.1, NP_658912.1
Form
Liquid
Purification
Antigen affinity purification
Recommend Usage
ELISA (1:32000)
Western Blot (0.5-1ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
RGS13 polyclonal antibody (Cat # PAB19639) (0.5 ug/mL) staining of human peripheral blood mononucleocyte lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — RGS13
Entrez GeneID
6003Protein Accession#
NP_658912.1Gene Name
RGS13
Gene Alias
MGC17173
Gene Description
regulator of G-protein signaling 13
Omim ID
607190Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the regulator of G protein signaling (RGS) family. RGS family members share similarity with S. cerevisiae SST2 and C. elegans egl-10 proteins, which contain a characteristic conserved RGS domain. RGS proteins accelerate GTPase activity of G protein alpha-subunits, thereby driving G protein into their inactive GDP-bound form, thus negatively regulating G protein signaling. RGS proteins have been implicated in the fine tuning of a variety of cellular events in response to G protein-coupled receptor activation. The biological function of this gene, however, is unknown. Two transcript variants encoding the same isoform exist. [provided by RefSeq
Other Designations
OTTHUMP00000033593|regulator of G-protein signalling 13
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