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GPC3 polyclonal antibody

  • Catalog # : PAB19582
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of GPC3.
  • Immunogen:
  • A synthetic peptide corresponding to C-terminus of human GPC3.
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 64
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Immunoaffinity purification
  • Recommend Usage:
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 10 mM PBS, pH 7.4 (1% BSA, 0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C. Do not freeze.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining of paraffin-embedded human liver carcinoma tissue section with GPC3 polyclonal antibody (Cat # PAB19582 ).
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
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  • Gene Information
  • Entrez GeneID:
  • 2719
  • Gene Name:
  • GPC3
  • Gene Alias:
  • DGSX,OCI-5,SDYS,SGB,SGBS,SGBS1
  • Gene Description:
  • glypican 3
  • Gene Summary:
  • Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000024058,OTTHUMP00000062492,glypican proteoglycan 3
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