MTA1 polyclonal antibody
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More Files
- More Functions
Western Blot (Tissue lysate)
Western blot analysis of tissue lysates with MTA1 polyclonal antibody (Cat # PAB19550).
Lane 1 : rat liver
Lane 2 : rat thymus
Lane 3 : rat small intestine
Lane 4 : rat spleen
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of paraffin embedded human breast cancer tissue section with MTA1 polyclonal antibody (Cat # PAB19550).
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of MTA1.
Immunogen
A synthetic peptide corresponding to amino acids at C-terminus of human MTA1.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Specificity
The synthetic peptide identical to the related mouse and rat sequence.
Form
Lyophilized
Purification
Immunoaffinity purification
Isotype
IgG
Recommend Usage
Western Blot (1 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
Lyophilized from 0.9 mg NaCl, 0.2 mg Na2HPO4 (5 mg BSA, 0.05 mg sodium azide, 0.05 mg Thimerosal)
Storage Instruction
Store at -20°C on dry atmosphere.
After reconstitution with 200 uL of deionized water and concentration will be 500 ug/mL, store at -20°C or lower.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide and thimerosal: POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of tissue lysates with MTA1 polyclonal antibody (Cat # PAB19550).
Lane 1 : rat liver
Lane 2 : rat thymus
Lane 3 : rat small intestine
Lane 4 : rat spleenImmunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical staining of paraffin embedded human breast cancer tissue section with MTA1 polyclonal antibody (Cat # PAB19550). -
Gene Info — MTA1
Entrez GeneID
9112Gene Name
MTA1
Gene Alias
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Gene Description
metastasis associated 1
Omim ID
603526Gene Ontology
HyperlinkGene Summary
This gene encodes a protein that was identified in a screen for genes expressed in metastatic cells, specifically, mammary adenocarcinoma cell lines. Expression of this gene has been correlated with the metastatic potential of at least two types of carcinomas although it is also expressed in many normal tissues. The role it plays in metastasis is unclear. It was initially thought to be the 70kD component of a nucleosome remodeling deacetylase complex, NuRD, but it is more likely that this component is a different but very similar protein. These two proteins are so closely related, though, that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. The profile and activity of this gene product suggest that it is involved in regulating transcription and that this may be accomplished by chromatin remodeling. [provided by RefSeq
Other Designations
metastasis associated gene 1 protein|metastasis associated protein
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Interactome
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Disease
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