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Last updated: 2016/12/4
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DES polyclonal antibody

  • Catalog # : PAB1953
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of DES.
  • Immunogen:
  • A synthetic peptide (conjugated with KLH) corresponding to residues surrounding T16 of human DES.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Protein A purification
  • Recommend Usage:
  • Western Blot (1:1000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of DES polyclonal antibody (Cat # PAB1953) in NCI-H460 cell line lysates (35 ug/lane).DES (arrow) was detected using the purified polyclonal antibody.
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Formalin-fixed and paraffin-embedded human hepatocarcinomareacted with DES polyclonal antibody (Cat # PAB1953), which was peroxidase-conjugated to the secondary antibody, followed by AEC staining.
    This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 1674
  • Protein Accession#:
  • NP_001918;P17661
  • Gene Name:
  • DES
  • Gene Alias:
  • CMD1I,CSM1,CSM2,FLJ12025,FLJ39719,FLJ41013,FLJ41793
  • Gene Description:
  • desmin
  • Gene Summary:
  • This gene encodes a muscle-specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in this gene are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000064865,intermediate filament protein
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