CA1 polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of whole cell extracts with CA1 polyclonal antibody (Cat # PAB19518).
Lane 1, MCF-7
Lane 2, Smmc
Lane 3, A-549
Lane 4, Jurkat
Lane 5, Raji
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of CA1.
Immunogen
A synthetic peptide corresponding to amino acids at N-terminus of human CA1.
Host
Rabbit
Reactivity
Human, Rat
Specificity
It different from the mouse sequence by one amino acid.
Form
Lyophilized
Purification
Immunoaffinity purification
Isotype
IgG
Recommend Usage
Western Blot (1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
Lyophilized from 0.9 mg NaCl, 0.2 mg Na2HPO4 (5 mg BSA, 0.05 mg sodium azide, 0.05 mg Thimerosal)
Storage Instruction
Store at -20°C on dry atmosphere.
After reconstitution with 200 uL of deionized water and concentration will be 500 ug/mL, store at -20°C or lower.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide and thimerosal: POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of whole cell extracts with CA1 polyclonal antibody (Cat # PAB19518).
Lane 1, MCF-7
Lane 2, Smmc
Lane 3, A-549
Lane 4, Jurkat
Lane 5, Raji -
Gene Info — CA1
Entrez GeneID
759Gene Name
CA1
Gene Alias
Car1
Gene Description
carbonic anhydrase I
Omim ID
114800Gene Ontology
HyperlinkGene Summary
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA1 is closely linked to CA2 and CA3 genes on chromosome 8, and it encodes a cytosolic protein which is found at the highest level in erythrocytes. Variants of this gene have been described in some populations. Multiple alternatively spliced variants, encoding the same protein, have been identified. Transcript variants of CA1 utilizing alternative polyA_sites have been described in literature. [provided by RefSeq
Other Designations
carbonic dehydratase
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Interactome
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Pathway
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Disease
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