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CASP7 polyclonal antibody

  • Catalog # : PAB19506
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of CASP7.
  • Immunogen:
  • A synthetic peptide corresponding to amino acids at middle region of human CASP7.
  • Host:
  • Rabbit
  • Reactivity:
  • Human, Mouse, Rat
  • Specificity:
  • It different from the related mouse and rat sequence by two amino acids.
  • Form:
  • Lyophilized
  • Purification:
  • Immunoaffinity purification
  • Isotype:
  • IgG
  • Recommend Usage:
  • Western Blot (1 ug/mL)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • Lyophilized from 0.9 mg NaCl, 0.2 mg Na2HPO4 (5 mg BSA, 0.05 mg sodium azide, 0.05 mg Thimerosal)
  • Storage Instruction:
  • Store at -20°C on dry atmosphere.
    After reconstitution with 200 uL of deionized water and concentration will be 500 ug/mL, store at -20°C or lower.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide and thimerosal: POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of whole cell extracts with CASP7 polyclonal antibody (Cat # PAB19506).
    Lane 1, HeLa
    Lane 2, MCF-7
    Lane 3, SMMC
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Gene Information
  • Entrez GeneID:
  • 840
  • Gene Name:
  • CASP7
  • Gene Alias:
  • CMH-1,ICE-LAP3,MCH3
  • Gene Description:
  • caspase 7, apoptosis-related cysteine peptidase
  • Gene Summary:
  • This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of this caspase is cleaved by caspase 3 and 10. It is activated upon cell death stimuli and induces apoptosis. Alternative splicing results in four transcript variants, encoding three distinct isoforms. [provided by RefSeq
  • Other Designations:
  • ICE-like apoptotic protease 3,Lice2 alpha/beta/gamma,OTTHUMP00000020510,OTTHUMP00000020511,OTTHUMP00000020512,OTTHUMP00000020514,apoptotic protease MCH-3,caspase 7,caspase 7 isoform delta,caspase 7, apoptosis-related cysteine protease
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