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GAD2 polyclonal antibody

  • Catalog # : PAB19504
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of GAD2.
  • Immunogen:
  • A synthetic peptide corresponding to amino acids at N-terminus of human GAD2.
  • Host:
  • Rabbit
  • Reactivity:
  • Rat
  • Specificity:
  • It identical to the related mouse and rat sequence.
  • Form:
  • Lyophilized
  • Purification:
  • Immunoaffinity purification
  • Isotype:
  • IgG
  • Recommend Usage:
  • Western Blot (1 ug/mL)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • Lyophilized from 0.9 mg NaCl, 0.2 mg Na2HPO4 (5 mg BSA, 0.05 mg sodium azide, 0.05 mg Thimerosal)
  • Storage Instruction:
  • Store at -20°C on dry atmosphere.
    After reconstitution with 200 uL of deionized water and concentration will be 500 ug/mL, store at -20°C or lower.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide and thimerosal: POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining of paraffin-embedded rat brain tissue section with GAD2 polyclonal antibody (Cat # PAB19504).
  • Application Image
  • Western Blot
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 2572
  • Gene Name:
  • GAD2
  • Gene Alias:
  • GAD65,MGC161605,MGC161607
  • Gene Description:
  • glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
  • Gene Summary:
  • This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq
  • Other Designations:
  • Glutamate decarboxylase-2 (pancreas),OTTHUMP00000019335,OTTHUMP00000019336,glutamate decarboxylase 2,glutamate decarboxylase 2 (pancreatic islets and brain, 65kD)
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