Western blot analysis of tissue and cell extracts with APOD polyclonal antibody (Cat # PAB19500). Lane 1, rat liver tissue lysate. Lane 2, rat small intestine tissue lysate. Lane 3, rat brain tissue lysate. Lane 4, rat testicular tissue lysate. Lane 5, MCF-7 whole cell lysate. Lane 6, HeLa whole cell lysate. Lane 7, SMMC whole cell lysate. Lane 8, PC-12 whole cell lysate. Lane 9, COLO 320 whole cell lystae.
This gene encodes a component of high density lipoprotein that has no marked similarity to other apolipoprotein sequences. It has a high degree of homology to plasma retinol-binding protein and other members of the alpha 2 microglobulin protein superfamily of carrier proteins, also known as lipocalins. This glycoprotein is closely associated with the enzyme lecithin:cholesterol acyltransferase - an enzyme involved in lipoprotein metabolism. [provided by RefSeq