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ITGAV polyclonal antibody

  • Catalog # : PAB19487
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of ITGAV.
  • Immunogen:
  • A synthetic peptide corresponding to amino acids at C-terminus of human ITGAV.
  • Host:
  • Rabbit
  • Reactivity:
  • Human, Rat
  • Specificity:
  • It identical to the related mouse and rat sequence.
  • Form:
  • Lyophilized
  • Purification:
  • Immunoaffinity purification
  • Isotype:
  • IgG
  • Recommend Usage:
  • Western Blot (1 ug/mL)
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1 ug/mL)
    Immunocytochemistry (1 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • Lyophilized from 0.9 mg NaCl, 0.2 mg Na2HPO4 (5 mg BSA, 0.05 mg sodium azide, 0.05 mg Thimerosal)
  • Storage Instruction:
  • Store at -20°C on dry atmosphere.
    After reconstitution with 200 uL of deionized water and concentration will be 500 ug/mL, store at -20°C or lower.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide and thimerosal: POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot
  • Western Blot
  • Western blot analysis of tissue and cell extracts with ITGAV polyclonal antibody (Cat # PAB19487).
    Lane 1, rat spleen tissue lysate.
    Lane 2, rat pancreas tissue lysate.
    Lane 3, rat brain tissue lysate.
    Lane 4, rat liver tissue lysate.
    Lane 5, MM231 whole cell lysate.
    Lane 6, HeLa whole cell lysate.
    Lane 7, CEM whole cell lysate.
    Lane 8, COLO 320 whole cell lysate.
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical staining of paraffin-embedded human breast cancer tissue section with ITGAV polyclonal antibody (Cat # PAB19487).
  • Immunocytochemistry
  • Application Image
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Immunocytochemistry
  • Gene Information
  • Entrez GeneID:
  • 3685
  • Gene Name:
  • Gene Alias:
  • CD51,DKFZp686A08142,MSK8,VNRA
  • Gene Description:
  • integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)
  • Gene Summary:
  • ITAGV encodes integrin alpha chain V. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The I-domain containing integrin alpha V undergoes post-translational cleavage to yield disulfide-linked heavy and light chains, that combine with multiple integrin beta chains to form different integrins. Among the known associating beta chains (beta chains 1,3,5,6, and 8; 'ITGB1', 'ITGB3', 'ITGB5', 'ITGB6', and 'ITGB8'), each can interact with extracellular matrix ligands; the alpha V beta 3 integrin, perhaps the most studied of these, is referred to as the Vitronectin receptor (VNR). In addition to adhesion, many integrins are known to facilitate signal transduction. Alternative splicing results in multiple transcript variants. [provided by RefSeq
  • Other Designations:
  • Integrin, alpha-V (vitronectin receptor, alpha polypeptide),antigen identified by monoclonal antibody L230,integrin alpha-V
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