GRIA1 polyclonal antibody
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of GRIA1.
Immunogen
A synthetic peptide corresponding to internal region of human GRIA1.
Sequence
C-KIMQQWKNSDARD
Host
Goat
Theoretical MW (kDa)
102
Reactivity
Human, Mouse, Rat
Form
Liquid
Purification
Ammonium sulfate precipitation
Recommend Usage
ELISA (1:1600)
Western Blot (0.1-0.3 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
GRIA1 polyclonal antibody (Cat # PAB19480)(0.1 ug/mL) staining of human cerebellum (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — GRIA1
Entrez GeneID
2890Protein Accession#
NP_000818.2;NP_001107655.1Gene Name
GRIA1
Gene Alias
GLUH1, GLUR1, GLURA, HBGR1, MGC133252
Gene Description
glutamate receptor, ionotropic, AMPA 1
Omim ID
138248Gene Ontology
HyperlinkGene Summary
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes with multiple subunits, each possessing transmembrane regions, and all arranged to form a ligand-gated ion channel. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. This gene belongs to a family of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) receptors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
AMPA 1
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Interactome
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Pathway
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Disease
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