MTHFD1L polyclonal antibody
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More Files
- More Functions
Western Blot (Tissue lysate)
MTHFD1L polyclonal antibody (Cat # PAB19473)(0.1 ug/mL) staining of human cerebellum (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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Specification
Product Description
Goat polyclonal antibody raised against synthetic peptide of MTHFD1L.
Immunogen
A synthetic peptide corresponding to internal region of human MTHFD1L.
Sequence
C-DTNDRFLRKITIGQ
Host
Goat
Theoretical MW (kDa)
106
Reactivity
Human
Form
Liquid
Purification
Ammonium sulfate precipitation
Recommend Usage
ELISA (1:3200)
Western Blot (0.1-0.3 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
MTHFD1L polyclonal antibody (Cat # PAB19473)(0.1 ug/mL) staining of human cerebellum (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.Enzyme-linked Immunoabsorbent Assay
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Gene Info — MTHFD1L
Entrez GeneID
25902Protein Accession#
NP_056255.2Gene Name
MTHFD1L
Gene Alias
DKFZp586G1517, FLJ21145, FTHFSDC1, MTC1THFS, dJ292B18.2
Gene Description
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
Omim ID
611427Gene Ontology
HyperlinkGene Summary
One-carbon substituted forms of tetrahydrofolate (THF) are involved in the de novo synthesis of purines and thymidylate and support cellular methylation reactions through the regeneration of methionine from homocysteine. MTHFD1L is an enzyme involved in THF synthesis in mitochondria (Christensen et al., 2005 [PubMed 15611115]).[supplied by OMIM
Other Designations
OTTHUMP00000017418|formyltetrahydrofolate synthetase domain containing 1|mitochondrial C1-tetrahydrofolate synthase|mitochondrial C1-tetrahydrofolate synthetase
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Interactome
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Pathway
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Disease
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