ZNF346 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of ZNF346.
Immunogen
A synthetic peptide corresponding to 20 amino acids near C-terminus of human ZNF346.
Host
Rabbit
Reactivity
Human, Mouse
Specificity
ZNF346 antibody is predicted to not cross-react with other ZNF family members. Three isoforms of ZNF346 are known to exist; this antibody will recognize the two longest isoforms.
Form
Liquid
Purification
Peptide affinity purification
Concentration
1 mg/mL
Recommend Usage
Western Blot (1-2 ug/mL)
Immunohistochemistry (5 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of ZNF346 in human kidney tissue lysate with ZNF346 polyclonal antibody (Cat # PAB19456) at 1 ug/mL (lane 1) and 2 ug/mL (lane 2).Immunohistochemistry
Immunohistochemical staining of human kidney cells with ZNF346 polyclonal antibody (Cat # PAB19456) at 5 ug/mL.Enzyme-linked Immunoabsorbent Assay
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Gene Info — ZNF346
Entrez GeneID
23567Protein Accession#
NP_036411Gene Name
ZNF346
Gene Alias
DKFZp547M223, JAZ, Zfp346
Gene Description
zinc finger protein 346
Omim ID
605308Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a nucleolar, zinc finger protein that preferentially binds to double-stranded (ds) RNA or RNA/DNA hybrids, rather than DNA alone. Mutational studies indicate that the zinc finger domains are not only essential for dsRNA binding, but are also required for its nucleolar localization. The encoded protein may be involved in cell growth and survival. [provided by RefSeq
Other Designations
double-stranded RNA-binding zinc finger protein JAZ
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