TYW1 polyclonal antibody
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More Files
- More Functions
Western Blot (Tissue lysate)
Western blot analysis of TYW1 in human lung tissue lysate with TYW1 polyclonal antibody (Cat # PAB19453) at 1 ug/mL.
Immunohistochemistry
Immunohistochemical staining of human lung cells with TYW1 polyclonal antibody (Cat # PAB19453) at 5 ug/mL.
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of TYW1.
Immunogen
A synthetic peptide corresponding to 19 amino acids near C-terminus of human TYW1.
Host
Rabbit
Reactivity
Human, Rat
Specificity
TYW1 antibody is predicted to not cross-react with other TYW protein family members. At least three isoforms of TYW1 are known to exist; this antibody will only detect the two larger isoforms.
Form
Liquid
Purification
Peptide affinity purification
Concentration
1 mg/mL
Recommend Usage
Western Blot (1 ug/mL)
Immunohistochemistry (5 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of TYW1 in human lung tissue lysate with TYW1 polyclonal antibody (Cat # PAB19453) at 1 ug/mL.Immunohistochemistry
Immunohistochemical staining of human lung cells with TYW1 polyclonal antibody (Cat # PAB19453) at 5 ug/mL.Enzyme-linked Immunoabsorbent Assay
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Gene Info — TYW1
Entrez GeneID
55253Protein Accession#
NP_060734Gene Name
TYW1
Gene Alias
FLJ10900, MGC23001, MGC60291, RSAFD1, TYW1A, YPL207W
Gene Description
tRNA-yW synthesizing protein 1 homolog (S. cerevisiae)
Omim ID
611243Gene Ontology
HyperlinkGene Summary
Wybutosine (yW) is a hypermodified guanosine at the 3-prime position adjacent to the anticodon of phenylalanine tRNA that stabilizes codon-anticodon interactions during decoding on the ribosome. TYW1 is the human homolog of a yeast gene essential for yW synthesis (Noma and Suzuki, 2006).[supplied by OMIM
Other Designations
radical S-adenosyl methionine and flavodoxin domains 1|tRNA-yW synthesizing protein 1 homolog A
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Interactome
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Disease
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