DYRK2 polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of DYRK2 in 293 cell lysate with DYRK2 polyclonal antibody (Cat # PAB19451) at 1 ug/mL (lane 1) and 2 ug/mL (lane 2).
Immunocytochemistry
Immunocytochemical staining of 293 cells with DYRK2 polyclonal antibody (Cat # PAB19451) at 10 ug/mL.
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of DYRK2.
Immunogen
A synthetic peptide corresponding to 18 amino acids near C-terminus of human DYRK2.
Host
Rabbit
Reactivity
Human
Specificity
Two isoforms of DYRK2 are known to exist; this antibody will recognize both isoforms. DYRK2 antibody will not cross-react with other DYRK family members.
Form
Liquid
Purification
Peptide affinity purification
Concentration
1 mg/mL
Recommend Usage
Western Blot (1-2 ug/mL)
Immunocytochemistry (10 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of DYRK2 in 293 cell lysate with DYRK2 polyclonal antibody (Cat # PAB19451) at 1 ug/mL (lane 1) and 2 ug/mL (lane 2).Immunocytochemistry
Immunocytochemical staining of 293 cells with DYRK2 polyclonal antibody (Cat # PAB19451) at 10 ug/mL.Enzyme-linked Immunoabsorbent Assay
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Gene Info — DYRK2
Entrez GeneID
8445Protein Accession#
NP_006473Gene Name
DYRK2
Gene Alias
FLJ21217, FLJ21365
Gene Description
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2
Omim ID
603496Gene Ontology
HyperlinkGene Summary
DYRK2 belongs to a family of protein kinases whose members are presumed to be involved in cellular growth and/or development. The family is defined by structural similarity of their kinase domains and their capability to autophosphorylate on tyrosine residues. DYRK2 has demonstrated tyrosine autophosphorylation and catalyzed phosphorylation of histones H3 and H2B in vitro. Two isoforms of DYRK2 have been isolated. The predominant isoform, isoform 1, lacks a 5' terminal insert. [provided by RefSeq
Other Designations
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