KL polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of KL.
Immunogen
A synthetic peptide corresponding to 16 amino acids near internal region of human KL.
The immunogen is located within amino acids 410-460 of KLOTHO.Host
Rabbit
Reactivity
Human, Mouse, Rat
Specificity
Three isoforms of KLOTHO are known to exist.
Form
Liquid
Purification
Peptide affinity purification
Concentration
1 mg/mL
Recommend Usage
Western Blot (1-2 ug/mL)
Immunohistochemistry (2.5 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide).
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of KLOTHO in rat heart tissue lysate with KL polyclonal antibody (Cat # PAB19446) at 1 ug/mL (lane 1) and 2 ug/mL (lane 2).Immunohistochemistry
Immunohistochemical staining of mouse heart cells with KL polyclonal antibody (Cat # PAB19446) at 2.5 ug/mL.Enzyme-linked Immunoabsorbent Assay
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Gene Info — KL
Entrez GeneID
9365Protein Accession#
NP_004786Gene Name
KL
Gene Alias
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Gene Description
klotho
Omim ID
604824Gene Ontology
HyperlinkGene Summary
This gene encodes a type-I membrane protein that is related to beta-glucosidases. Reduced production of this protein has been observed in patients with chronic renal failure (CRF), and this may be one of the factors underlying the degenerative processes (e.g., arteriosclerosis, osteoporosis, and skin atrophy) seen in CRF. Also, mutations within this protein have been associated with ageing and bone loss. [provided by RefSeq
Other Designations
OTTHUMP00000018796
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Interactome
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Disease
- Acute Disease
- Aging
- Alzheimer disease
- Anemia
- Angina Pectoris
- Atherosclerosis
- Brain Ischemia
- Breast Neoplasms
- Calcinosis
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