SLC39A8 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of SLC39A8.
Immunogen
A synthetic peptide corresponding to 18 amino acids near C-terminus of human SLC39A8.
Host
Rabbit
Reactivity
Human
Specificity
This antibody is predicted to not cross-react with other ZIP family members.
Form
Liquid
Purification
Peptide affinity purification
Concentration
1 mg/mL
Recommend Usage
Western Blot (1-2 ug/mL)
Immunohistochemistry (5 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of ZIP8 in human spleen tissue lysate with SLC39A8 polyclonal antibody (Cat # PAB19445) at 1 ug/mL (lane 1) and 2 ug/mL (lane 2).Immunohistochemistry
Immunohistochemical staining of human spleen cells with SLC39A8 polyclonal antibody (Cat # PAB19445) at 5 ug/mL.Enzyme-linked Immunoabsorbent Assay
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Gene Info — SLC39A8
Entrez GeneID
64116Protein Accession#
NP_071437Gene Name
SLC39A8
Gene Alias
BIGM103, LZT-Hs6, PP3105, ZIP8
Gene Description
solute carrier family 39 (zinc transporter), member 8
Omim ID
608732Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the SLC39 family of solute-carrier genes, which show structural characteristics of zinc transporters. The encoded protein is glycosylated and found in the plasma membrane and mitochondria, and functions in the cellular import of zinc at the onset of inflammation. It is also thought to be the primary transporter of the toxic cation cadmium, which is found in cigarette smoke. Multiple transcript variants encoding different isoforms have been found for this gene. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq
Other Designations
BCG induced integral membrane protein BIGM103|LIV-1 subfamily of ZIP zinc transporter 6|Zrt- and Irt-like protein 8|solute carrier family 39 (metal ion transporter), member 8|zinc transporter ZIP8
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Interactome
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Disease
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