Western blot analysis of TYW4 in rat brain tissue lysate with LCMT2 polyclonal antibody (Cat # PAB19442) at 1 ug/mL. Lane 1 : The absence of blocking peptide. Lane 2 : The presence of blocking peptide.
Immunohistochemical staining of mouse brain cells with LCMT2 polyclonal antibody (Cat # PAB19442) at 5 ug/mL.
The protein encoded by this intronless gene belongs to the highly variable methyltransferase superfamily. This gene is the inferred homolog of the Saccharomyces cerevisiae carboxymethyltransferase gene PPM2 that is essential for the synthesis of the hypermodified guanosine Wybutosine (yW). [provided by RefSeq
OTTHUMP00000161298,tRNA-Wybutosine-synthesizing protein 4,tRNA-yW synthesizing protein 4