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Last updated: 2016/12/4

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ROCK1 polyclonal antibody

  • Catalog # : PAB19432
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of ROCK1.
  • Immunogen:
  • A synthetic peptide corresponding to 15 amino acids near N-terminus of human ROCK1.
  • Host:
  • Rabbit
  • Reactivity:
  • Human, Mouse, Rat
  • Specificity:
  • ROCK1 antibody is predicted to not cross-react with other ROCK protein family members.
  • Form:
  • Liquid
  • Purification:
  • Peptide affinity purification
  • Concentration:
  • 1 mg/mL
  • Recommend Usage:
  • Western Blot (1 ug/mL)
    Immunocytochemistry (10 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.02% sodium azide)
  • Storage Instruction:
  • Store at 4°C for three months. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of ROCK1 in 293 cell lysate with ROCK1 polyclonal antibody (Cat # PAB19432) at 1 ug/mL.
    Lane 1 : The absence of blocking peptide.
    Lane 2 : The presence of blocking peptide.
  • Immunocytochemistry
  • Immunocytochemistry
  • Immunocytochemical staining of 293 cells with ROCK1 polyclonal antibody (Cat # PAB19432) at 10 ug/mL.
  • ELISA
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 6093
  • Gene Name:
  • ROCK1
  • Gene Alias:
  • MGC131603,MGC43611,P160ROCK,PRO0435
  • Gene Description:
  • Rho-associated, coiled-coil containing protein kinase 1
  • Gene Summary:
  • This gene encodes a protein serine/threonine kinase that is activated when bound to the GTP-bound form of Rho. The small GTPase Rho regulates formation of focal adhesions and stress fibers of fibroblasts, as well as adhesion and aggregation of platelets and lymphocytes by shuttling between the inactive GDP-bound form and the active GTP-bound form. Rho is also essential in cytokinesis and plays a role in transcriptional activation by serum response factor. This protein, a downstream effector of Rho, phosphorylates and activates LIM kinase, which in turn, phosphorylates cofilin, inhibiting its actin-depolymerizing activity. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000162514,p160-ROCK
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