EZH1 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of EZH1.
Immunogen
A synthetic peptide corresponding to 18 amino acids near N-terminus of human EZH1.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Specificity
Multiple isoforms of EZH1 are known to exist. EZH1 antibody is predicted to not cross-react with EZH2.
Form
Liquid
Purification
Peptide affinity purification
Concentration
1 mg/mL
Recommend Usage
Western Blot (1-2 ug/mL)
Immunohistochemistry (5 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of EZH1 in mouse lung tissue lysate with EZH1 polyclonal antibody (Cat # PAB19418) at 1 ug/mL (lane 1) and 2 ug/mL (lane 2).Immunohistochemistry
Immunohistochemical staining of human lung cells with EZH1 polyclonal antibody (Cat # PAB19418) at 5 ug/mL.Enzyme-linked Immunoabsorbent Assay
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Gene Info — EZH1
Entrez GeneID
2145Protein Accession#
AAC50778Gene Name
EZH1
Gene Alias
KIAA0388
Gene Description
enhancer of zeste homolog 1 (Drosophila)
Omim ID
601674Gene Ontology
HyperlinkGene Summary
EZH1 is a component of a noncanonical Polycomb repressive complex-2 (PRC2) that mediates methylation of histone H3 (see MIM 602812) lys27 (H3K27) and functions in the maintenance of embryonic stem cell pluripotency and plasticity (Shen et al., 2008 [PubMed 19026780]).[supplied by OMIM
Other Designations
enhancer of zeste homolog 1
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Interactome
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Disease
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