TSN polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of TSN.
Immunogen
A synthetic peptide corresponding to 20 amino acids near C-terminus of human TSN.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Specificity
At least two isoforms of TSN are known to exist; this antibody will detect both.
Form
Liquid
Purification
Peptide affinity purification
Concentration
1 mg/mL
Recommend Usage
Western Blot (0.5-1 ug/mL)
Immunohistochemistry (5 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of TSN in rat lung tissue lysate with TSN polyclonal antibody (Cat # PAB19396) at (1) 0.5 and (2) 1 ug/mL.Immunohistochemistry
Immunohistochemical staining of human lung cells with TSN polyclonal antibody (Cat # PAB19396) at 5 ug/mL.Enzyme-linked Immunoabsorbent Assay
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Gene Info — TSN
Entrez GeneID
7247Protein Accession#
NP_004613Gene Name
TSN
Gene Alias
BCLF-1, REHF-1, TRSLN
Gene Description
translin
Omim ID
600575Gene Ontology
HyperlinkGene Summary
This gene encodes a DNA-binding protein which specifically recognizes conserved target sequences at the breakpoint junction of chromosomal translocations. Translin polypeptides form a multimeric structure that is responsible for its DNA-binding activity. Recombination-associated motifs and translin-binding sites are present at recombination hotspots and may serve as indicators of breakpoints in genes which are fused by translocations. These binding activities may play a crucial role in chromosomal translocation in lymphoid neoplasms. [provided by RefSeq
Other Designations
recombination hotspot associated factor|recombination hotspot-binding protein
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