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Last updated: 2017/7/23

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SPTLC2 polyclonal antibody

  • Catalog # : PAB19384
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of SPTLC2.
  • Immunogen:
  • A synthetic peptide corresponding to 15 amino acids near C-terminus of human SPTLC2.
  • Host:
  • Rabbit
  • Reactivity:
  • Human, Mouse, Rat
  • Specificity:
  • At least three isoforms of SPTLC2 are known to exist; this antibody will not detect isoform b. This antibody is predicted to not cross-react with SPT1.
  • Form:
  • Liquid
  • Purification:
  • Peptide affinity purification
  • Concentration:
  • 1 mg/mL
  • Recommend Usage:
  • Western Blot (1 ug/mL)
    Immunocytochemistry (10 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.02% sodium azide)
  • Storage Instruction:
  • Store at 4°C for three months. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot analysis of SPTLC2 in NIH/3T3 cell lysate with SPTLC2 polyclonal antibody (Cat # PAB19384) at 1 ug/mL in (1) the absence and (2) the presence of blocking peptide.
  • Immunocytochemistry
  • Immunocytochemistry
  • Immunocytochemical staining of 3T3 cells with SPTLC2 polyclonal antibody (Cat # PAB19384) at 10 ug/mL.
  • ELISA
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 9517
  • Gene Name:
  • SPTLC2
  • Gene Alias:
  • KIAA0526,LCB2,SPT2
  • Gene Description:
  • serine palmitoyltransferase, long chain base subunit 2
  • Gene Summary:
  • This gene encodes a long chain base subunit of serine palmitoyltransferase. Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal-5-prime-phosphate-dependent condensation of L-serine and palmitoyl-CoA to 3-oxosphinganine. Mutations in this gene were identified in patients with hereditary sensory neuropathy type I. Alternatively spliced variants encoding different isoforms have been identified. [provided by RefSeq
  • Other Designations:
  • serine palmitoyltransferase, subunit II
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