SLC39A14 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of SLC39A14.
Immunogen
A synthetic peptide corresponding to 16 amino acids near internal region of human SLC39A14.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Specificity
At least three isoforms of SLC39A14 are known to exist; this antibody will detect both isoforms. This antibody is predicted to not cross-react with other ZIP family members.
Form
Liquid
Purification
Peptide affinity purification
Concentration
1 mg/mL
Recommend Usage
Western Blot (1-2 ug/mL)
Immunohistochemistry (2.5 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of SLC39A14 in human spleen tissue lysate with SLC39A14 polyclonal antibody (Cat # PAB19383) at (1) 1 and (2) 2 ug/mL.Immunohistochemistry
Immunohistochemical staining of mouse liver cells with SLC39A14 polyclonal antibody (Cat # PAB19383) at 2.5 ug/mL.Enzyme-linked Immunoabsorbent Assay
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Gene Info — SLC39A14
Entrez GeneID
23516Protein Accession#
NP_001128625Gene Name
SLC39A14
Gene Alias
KIAA0062, LZT-Hs4, ZIP14, cig19
Gene Description
solute carrier family 39 (zinc transporter), member 14
Omim ID
608736Gene Ontology
HyperlinkGene Summary
Zinc is an essential cofactor for hundreds of enzymes. It is involved in protein, nucleic acid, carbohydrate, and lipid metabolism, as well as in the control of gene transcription, growth, development, and differentiation. SLC39A14 belongs to a subfamily of proteins that show structural characteristics of zinc transporters (Taylor and Nicholson, 2003 [PubMed 12659941]).[supplied by OMIM
Other Designations
LIV-1 subfamily of ZIP zinc transporter 4|Zinc transporter ZIP14|Zrt-, Irt-like protein 14|solute carrier family 39 (metal ion transporter), member 14
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Interactome
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Disease
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Publication Reference
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Involvement of metal transporters in the intestinal uptake of cadmium.
Hisayoshi Ohta, Kenichi Ohba.
The Journal of Toxicological Sciences 2020 Jan; 45(9):539.
Application:IHC-P, Rat, Rat duodenum.
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Involvement of metal transporters in the intestinal uptake of cadmium.
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