RCE1 polyclonal antibody
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
-
Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of RCE1.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human RCE1.
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Protein A purification
Recommend Usage
Western Blot (1:1000)
Immunohistochemistry (1:50-100)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Western Blot (Transfected lysate)
Western blot analysis of RCE1 (arrow) using RCE1 polyclonal antibody (Cat # PAB1938).
293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the RCE1 gene (Lane 2).Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Formalin-fixed and paraffin-embedded human breast cancer tissue reacted with RCE1 polyclonal antibody (Cat # PAB1938) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. -
Gene Info — RCE1
Entrez GeneID
9986Protein Accession#
NP_005124;Q9Y256Gene Name
RCE1
Gene Alias
FACE2, RCE1A, RCE1B
Gene Description
RCE1 homolog, prenyl protein peptidase (S. cerevisiae)
Omim ID
605385Gene Ontology
HyperlinkGene Summary
This gene encodes an integral membrane protein which is classified as a member of the metalloproteinase family. This enzyme is thought to function in the maintenance and processing of CAAX-type prenylated proteins. [provided by RefSeq
Other Designations
RCE1 homolog, prenyl protein protease|farnesylated protein-converting enzyme 2|prenyl protein peptidase RCE1|prenyl protein-specific endoprotease 2
-
Interactome
-
Publication Reference
-
A carboxyl-terminal interaction of lamin B1 is dependent on the CAAX endoprotease Rce1 and carboxymethylation.
Maske CP, Hollinshead MS, Higbee NC, Bergo MO, Young SG, Vaux DJ.
The Journal of Cell Biolog 2003 Sep; 162(7):1223.
-
Human Ras converting enzyme endoproteolytic specificity at the P2' and P3' positions of K-Ras-derived peptides.
Hollander IJ, Frommer E, Aulabaugh A, Mallon R.
Biochimica et Biophysica Acta 2003 Jun; 1649(1):24.
-
Identification and chromosomal location of two human genes encoding enzymes potentially involved in proteolytic maturation of farnesylated proteins.
Freije JM, Blay P, Pendas AM, Cadinanos J, Crespo P, Lopez-Otin C.
Genomics 1999 Jun; 58(3):270.
-
A carboxyl-terminal interaction of lamin B1 is dependent on the CAAX endoprotease Rce1 and carboxymethylation.
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com