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Last updated: 2016/11/27

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NUMB polyclonal antibody

  • Catalog # : PAB19370
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of NUMB.
  • Immunogen:
  • A synthetic peptide corresponding to 17 amino acids near C-terminus of human NUMB.
  • Host:
  • Rabbit
  • Reactivity:
  • Human, Mouse, Rat
  • Specificity:
  • At least four isoforms of NUMB are known to exist; this antibody will detect all of them.
  • Form:
  • Liquid
  • Purification:
  • Peptide affinity purification
  • Concentration:
  • 1 mg/mL
  • Recommend Usage:
  • Western Blot (0.25-0.5 ug/mL)
    Immunohistochemistry (5 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.02% sodium azide)
  • Storage Instruction:
  • Store at 4°C for three months. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • Western blot analysis of NUMB in mouse lung tissue lysate with NUMB polyclonal antibody (Cat # PAB19370) at (1) 0.25 and (2) 0.5 ug/mL.
  • Immunohistochemistry
  • Immunohistochemistry
  • Immunohistochemical staining of human lung cells with NUMB polyclonal antibody (Cat # PAB19370) at 5 ug/mL.
  • ELISA
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 8650
  • Gene Name:
  • NUMB
  • Gene Alias:
  • S171
  • Gene Description:
  • numb homolog (Drosophila)
  • Gene Summary:
  • The protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • numb homolog
  • Interactome
  • Interactome
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