AP3M1 polyclonal antibody
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More Files
- More Functions
Western Blot (Tissue lysate)
Western blot analysis of AP3M1 in human brain tissue lysate with AP3M1 polyclonal antibody (Cat # PAB19366) at (1) 1 and (2) 2 ug/mL.
Immunohistochemistry
Immunohistochemical staining of mouse brain cells with AP3M1 polyclonal antibody (Cat # PAB19366) at 5 ug/mL.
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of AP3M1.
Immunogen
A synthetic peptide corresponding to 15 amino acids near C-terminus of human AP3M1.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Specificity
AP3M1 antibody may cross-react with AP3M2.
Form
Liquid
Purification
Peptide affinity purification
Concentration
1 mg/mL
Recommend Usage
Western Blot (1-2 ug/mL)
Immunohistochemistry (5 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of AP3M1 in human brain tissue lysate with AP3M1 polyclonal antibody (Cat # PAB19366) at (1) 1 and (2) 2 ug/mL.Immunohistochemistry
Immunohistochemical staining of mouse brain cells with AP3M1 polyclonal antibody (Cat # PAB19366) at 5 ug/mL.Enzyme-linked Immunoabsorbent Assay
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Gene Info — AP3M1
Entrez GeneID
26985Protein Accession#
NP_036227Gene Name
AP3M1
Gene Alias
MGC22164
Gene Description
adaptor-related protein complex 3, mu 1 subunit
Omim ID
610366Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is the medium subunit of AP-3, which is an adaptor-related protein complex associated with the Golgi region as well as more peripheral intracellular structures. AP-3 facilitates the budding of vesicles from the Golgi membrane and may be directly involved in protein sorting to the endosomal/lysosomal system. AP-3 is a heterotetrameric protein complex composed of two large subunits (delta and beta3), a medium subunit (mu3), and a small subunit (sigma 3). Mutations in one of the large subunits of AP-3 have been associated with the Hermansky-Pudlak syndrome, a genetic disorder characterized by defective lysosome-related organelles. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq
Other Designations
AP-3 adapter complex mu3A subunit|OTTHUMP00000019859|OTTHUMP00000019860|clathrin adaptor complex AP3, mu-3A subunit|mu-adaptin 3A
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Interactome
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Pathway
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Disease
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