NLRP14 polyclonal antibody
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More Files
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Western Blot (Tissue lysate)
Western blot analysis of NLRP14 in rat brain tissue lysate with NLRP14 polyclonal antibody (Cat # PAB19311) at 1 ug/mL.
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Specification
Product Description
Rabbit polyclonal antibody rasied against synthetic peptide of NLRP14.
Immunogen
A synthetic peptide corresponding to 16 amino acids near N-terminus of human NLRP14.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Form
Liquid
Purification
Affinity purification
Concentration
1 mg/mL
Recommend Usage
Western blot (1-2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of NLRP14 in rat brain tissue lysate with NLRP14 polyclonal antibody (Cat # PAB19311) at 1 ug/mL.Enzyme-linked Immunoabsorbent Assay
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Gene Info — NLRP14
Entrez GeneID
338323Protein Accession#
NP_789792Gene Name
NLRP14
Gene Alias
CLR11.2, GC-LRR, NALP14, NOD5, PAN8
Gene Description
NLR family, pyrin domain containing 14
Omim ID
609665Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to the NALP protein family. Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). This protein may play a regulatory role in the innate immune system as similar family members belong to the signal-induced multiprotein complex, the inflammasome, that activates the pro-inflammatory caspases, caspase-1 and caspase-5. [provided by RefSeq
Other Designations
NACHT, LRR and PYD containing protein 14|NACHT, leucine rich repeat and PYD containing 14|nucleotide-binding oligomerization domain protein 5|nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 14
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Disease
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Publication Reference
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Mammalian oocytes store proteins for the early embryo on cytoplasmic lattices.
Ida M A Jentoft, Felix J B Bäuerlein, Luisa M Welp, Benjamin H Cooper, Arsen Petrovic, Chun So, Sarah Mae Penir, Antonio Z Politi, Yehor Horokhovskyi, Iina Takala, Heike Eckel, Rüdiger Moltrecht, Peter Lénárt, Tommaso Cavazza, Juliane Liepe, Nils Brose, Henning Urlaub, Rubén Fernández-Busnadiego, Melina Schuh.
Cell 2023 Nov; 186(24):5308.
Application：IF, Mouse, Mouse oocytes.
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Mammalian oocytes store proteins for the early embryo on cytoplasmic lattices.
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