NLRP12 polyclonal antibody
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More Files
- More Functions
Western Blot (Tissue lysate)
Western blot analysis of NLRP12 in human brain tissue lysate with NLRP12 polyclonal antibody (Cat # PAB19309) at 1 ug/mL.
Immunohistochemistry
Immunohistochemical staining of human brain cells with NLRP12 polyclonal antibody (Cat # PAB19309) at 5 ug/mL.
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Specification
Product Description
Rabbit polyclonal antibody rasied against synthetic peptide of NLRP12.
Immunogen
A synthetic peptide corresponding to 18 amino acids near N-terminus of human NLRP12.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Form
Liquid
Purification
Peptide affinity purification
Concentration
1 mg/mL
Recommend Usage
Western Blot (1 ug/mL)
Immunohistochemistry (5 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of NLRP12 in human brain tissue lysate with NLRP12 polyclonal antibody (Cat # PAB19309) at 1 ug/mL.Immunohistochemistry
Immunohistochemical staining of human brain cells with NLRP12 polyclonal antibody (Cat # PAB19309) at 5 ug/mL.Enzyme-linked Immunoabsorbent Assay
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Gene Info — NLRP12
Entrez GeneID
91662Protein Accession#
NP_653288Gene Name
NLRP12
Gene Alias
CLR19.3, FCAS2, NALP12, PAN6, PYPAF7, RNO, RNO2
Gene Description
NLR family, pyrin domain containing 12
Omim ID
609648Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the CATERPILLER family of cytoplasmic proteins. The encoded protein, which contains an N-terminal pyrin domain, a NACHT domain, a NACHT-associated domain, and a C-terminus leucine-rich repeat region, functions as an attenuating factor of inflammation by suppressing inflammatory responses in activated monocytes. Alternatively spliced transcript variants encoding distinct isoforms have been described but the full-length nature of some of these has not been determined. [provided by RefSeq
Other Designations
NACHT, LRR and PYD containing protein 12|NACHT, leucine rich repeat and PYD containing 12|OTTHUMP00000067226|PYRIN-containing APAF1-like protein 7|monarch 1|nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 12|regu
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Interactome
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Disease
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