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Last updated: 2017/2/26

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NLRP8 polyclonal antibody

  • Catalog # : PAB19306
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody rasied against synthetic peptide of NLRP8.
  • Immunogen:
  • A synthetic peptide corresponding to 16 amino acids near N-terminus of human NLRP8.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Affinity purification
  • Concentration:
  • 1 mg/mL
  • Recommend Usage:
  • Western blot (1-2 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.02% sodium azide)
  • Storage Instruction:
  • Store at 4°C for three months. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • Western blot analysis of NLRP8 in human colon tissue lysate with NLRP8 polyclonal antibody (Cat # PAB19306) at 1 ug/mL in (1) the absence and (2) the presence of blocking peptide.
  • ELISA
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Gene Name:
  • NLRP8
  • Gene Alias:
  • CLR19.2,NALP8,NOD16,PAN4
  • Gene Description:
  • NLR family, pyrin domain containing 8
  • Gene Summary:
  • NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP8, have an N-terminal pyrin (MEFV; MIM 608107) domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1 (MIM 606636), also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs are implicated in the activation of proinflammatory caspases (e.g., CASP1; MIM 147678) via their involvement in multiprotein complexes called inflammasomes (Tschopp et al., 2003 [PubMed 12563287]).[supplied by OMIM
  • Other Designations:
  • NACHT, LRR and PYD containing protein 8,NACHT, leucine rich repeat and PYD containing 8,nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 8
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