NLRP7 polyclonal antibody
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More Files
- More Functions
Western Blot (Tissue lysate)
Western blot analysis of NLRP7 in human brain tissue lysate with NLRP7 polyclonal antibody (Cat # PAB19305) at 1 ug/mL in (1) the absence and (2) the presence of blocking peptide.
Immunohistochemistry
Immunohistochemical staining of human brain cells with NLRP7 polyclonal antibody (Cat # PAB19305) at 10 ug/mL.
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Specification
Product Description
Rabbit polyclonal antibody rasied against synthetic peptide of NLRP7.
Immunogen
A synthetic peptide corresponding to 18 amino acids near N-terminus of human NLRP7.
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Peptide affinity purification
Concentration
1 mg/mL
Recommend Usage
Western Blot (1 ug/mL)
Immunohistochemistry (10 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of NLRP7 in human brain tissue lysate with NLRP7 polyclonal antibody (Cat # PAB19305) at 1 ug/mL in (1) the absence and (2) the presence of blocking peptide.Immunohistochemistry
Immunohistochemical staining of human brain cells with NLRP7 polyclonal antibody (Cat # PAB19305) at 10 ug/mL.Enzyme-linked Immunoabsorbent Assay
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Gene Info — NLRP7
Entrez GeneID
199713Protein Accession#
NP_631915Gene Name
NLRP7
Gene Alias
CLR19.4, FLJ94610, HYDM, MGC126470, MGC126471, NALP7, NOD12, PAN7, PYPAF3
Gene Description
NLR family, pyrin domain containing 7
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the NACHT, leucine rich repeat, and PYD containing (NLRP) protein family. It has an N-terminal pyrin domain, followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. NLRP proteins are implicated in the activation of proinflammatory caspases through multiprotein complexes called inflammasomes. This gene may act as a feedback regulator of caspase-1-dependent interleukin 1-beta secretion. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq
Other Designations
NACHT, LRR and PYD containing protein 7|NACHT, leucine rich repeat and PYD containing 7|PYRIN-containing Apaf1-like protein 3|nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 7
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Interactome
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Disease
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