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Last updated: 2017/2/19
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NLRP6 polyclonal antibody

  • Catalog # : PAB19304
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody rasied against synthetic peptide of NLRP6.
  • Immunogen:
  • A synthetic peptide corresponding to 16 amino acids near N-terminus of human NLRP6.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Peptide affinity purification
  • Concentration:
  • 1 mg/mL
  • Recommend Usage:
  • Western Blot (1 ug/mL)
    Immunofluorescence (20 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.02% sodium azide)
  • Storage Instruction:
  • Store at 4°C for three months. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • Western blot analysis of NLRP6 in mouse brain tissue lysate with NLRP6 polyclonal antibody (Cat # PAB19304) at 1 ug/mL in (1) the absence and (2) the presence of blocking peptide.
  • Immunofluorescence
  • Immunofluorescence
  • Immunofluorescencent staining of human brain cells with NLRP6 polyclonal antibody (Cat # PAB19304) at 20 ug/mL.
  • ELISA
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Gene Name:
  • NLRP6
  • Gene Alias:
  • CLR11.4,NALP6,PAN3,PYPAF5
  • Gene Description:
  • NLR family, pyrin domain containing 6
  • Gene Summary:
  • NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP6, have an N-terminal pyrin (MEFV; MIM 608107) domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1 (MIM 606636), also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs are implicated in the activation of proinflammatory caspases (e.g., CASP1; MIM 147678) via their involvement in multiprotein complexes called inflammasomes (Tschopp et al., 2003 [PubMed 12563287]).[supplied by OMIM
  • Other Designations:
  • NACHT, LRR and PYD containing protein 6,NACHT, leucine rich repeat and PYD containing 6,OTTHUMP00000147611,PYRIN-containing APAF1-like protein 5,nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domain containing 6
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