ALKBH2 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody rasied against synthetic peptide of ALKBH2.
Immunogen
A synthetic peptide corresponding to 15 amino acids near C-terminus of human ALKBH2.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Form
Liquid
Purification
Peptide affinity purification
Concentration
1 mg/mL
Recommend Usage
Western Blot (1-2 ug/mL)
Immunohistochemistry (10 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of ALKBH2 in human kidney tissue lysate with ALKBH2 polyclonal antibody (Cat # PAB19288) at (1) 1 and (2) 2 ug/mL.Immunohistochemistry
Immunohistochemical staining of human kidney cells with ALKBH2 polyclonal antibody (Cat # PAB19288) at 10 ug/mL.Enzyme-linked Immunoabsorbent Assay
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Gene Info — ALKBH2
Entrez GeneID
121642Protein Accession#
NP_001138847Gene Name
ALKBH2
Gene Alias
ABH2, MGC90512, hABH2
Gene Description
alkB, alkylation repair homolog 2 (E. coli)
Omim ID
610602Gene Ontology
HyperlinkGene Summary
The Escherichia coli AlkB protein protects against the cytotoxicity of methylating agents by repair of the specific DNA lesions generated in single-stranded DNA. ALKBH2 and ALKBH3 (MIM 610603) are E. coli AlkB homologs that catalyze the removal of 1-methyladenine and 3-methylcytosine (Duncan et al., 2002 [PubMed 12486230]).[supplied by OMIM
Other Designations
2OG-Fe(II) oxy DC1|alkB, alkylation repair homolog 2
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