RBBP8 polyclonal antibody
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More Files
- More Functions
Western Blot (Tissue lysate)
Western blot analysis of RBBP8 in mouse spleen tissue lysate with RBBP8 polyclonal antibody (Cat # PAB19252) at (1) 1 and (2) 2 ug/mL.
Immunohistochemistry
Immunohistochemistry of rat spleen tissue with RBBP8 polyclonal antibody (Cat # PAB19252) at 5 ug/mL.
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Specification
Product Description
Rabbit polyclonal antibody rasied against synthetic peptide of RBBP8.
Immunogen
A synthetic peptide corresponding to 14 amino acids near internal region of human RBBP8.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Form
Liquid
Purification
Peptide affinity purification
Concentration
1 mg/mL
Recommend Usage
Western Blot (1-2 ug/mL)
Immunohistochemistry (5 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of RBBP8 in mouse spleen tissue lysate with RBBP8 polyclonal antibody (Cat # PAB19252) at (1) 1 and (2) 2 ug/mL.Immunohistochemistry
Immunohistochemistry of rat spleen tissue with RBBP8 polyclonal antibody (Cat # PAB19252) at 5 ug/mL.Enzyme-linked Immunoabsorbent Assay
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Gene Info — RBBP8
Entrez GeneID
5932Protein Accession#
NP_976037Gene Name
RBBP8
Gene Alias
CTIP, RIM
Gene Description
retinoblastoma binding protein 8
Omim ID
604124Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a ubiquitously expressed nuclear protein. It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation. This protein complexes with transcriptional co-repressor CTBP. It is also associated with BRCA1 and is thought to modulate the functions of BRCA1 in transcriptional regulation, DNA repair, and/or cell cycle checkpoint control. It is suggested that this gene may itself be a tumor suppressor acting in the same pathway as BRCA1. Three transcript variants encoding two different isoforms have been found for this gene. More transcript variants exist, but their full-length natures have not been determined. [provided by RefSeq
Other Designations
CTBP-interacting protein|retinoblastoma-binding protein 8|retinoblastoma-interacting myosin-like
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Interactome
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Disease
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