CDC23 polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of K-562 cells with CDC23 polyclonal antibody (Cat # PAB19238) at (Lane 1) 1 and (Lane 2) 2 ug/mL dilution.
Immunocytochemistry
Immunocytochemical staining of K-562 cells with CDC23 polyclonal antibody (Cat # PAB19238) at 5 ug/mL dilution.
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Specification
Product Description
Rabbit polyclonal antibody rasied against synthetic peptide of CDC23.
Immunogen
A synthetic peptide corresponding to 17 amino acids near internal region of human CDC23.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Form
Liquid
Purification
Peptide affinity purification
Concentration
1 mg/mL
Recommend Usage
Western Blot (1-2 ug/mL)
Immunocytochemistry (5 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of K-562 cells with CDC23 polyclonal antibody (Cat # PAB19238) at (Lane 1) 1 and (Lane 2) 2 ug/mL dilution.Immunocytochemistry
Immunocytochemical staining of K-562 cells with CDC23 polyclonal antibody (Cat # PAB19238) at 5 ug/mL dilution.Enzyme-linked Immunoabsorbent Assay
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Gene Info — CDC23
Entrez GeneID
8697Protein Accession#
Q9UJX2Gene Name
CDC23
Gene Alias
APC8
Gene Description
cell division cycle 23 homolog (S. cerevisiae)
Omim ID
603462Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae Cdc23, a protein essential for cell cycle progression through the G2/M transition. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eukaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction. [provided by RefSeq
Other Designations
anaphase-promoting complex subunit 8|cell division cycle protein 23
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Interactome
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