MYBPC2 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody rasied against synthetic peptide of MYBPC2.
Immunogen
A synthetic peptide corresponding to 15 amino acids near C-terminus of human MYBPC2.
Host
Rabbit
Reactivity
Human, Mouse
Form
Liquid
Purification
Peptide affinity purification
Concentration
1 mg/mL
Recommend Usage
Western Blot (1-2 ug/mL)
Immunohistochemistry (5 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of mouse skeletal muscle tissue with MYBPC2 polyclonal antibody (Cat # PAB19214) at (Lane 1) 1 and (Lane 2) 2 ug/mL dilution.Immunohistochemistry
Immunohistochemical staining of mouse skeletal muscle tissue with MYBPC2 polyclonal antibody (Cat # PAB19214) at 5 ug/mL dilution.Enzyme-linked Immunoabsorbent Assay
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Gene Info — MYBPC2
Entrez GeneID
4606Protein Accession#
EAW71866Gene Name
MYBPC2
Gene Alias
MGC163408, MYBPC, MYBPCF
Gene Description
myosin binding protein C, fast type
Omim ID
160793Gene Ontology
HyperlinkGene Summary
O
Other Designations
fast-type muscle myosin-binding-protein C|myosin-binding protein C, fast-type
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Interactome
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Disease
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Publication Reference
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Down-regulated Smyd1 participated in the inhibition of myoblast differentiation induced by cigarette smoke extract.
Fang Li, Mengting Xu, Jianing Miao, Nengyin Hu, Ying Wang, Lili Wang. Fang Li a,b,c, Mengting Xu a,b,c, Jianing Miao a,b,c, Nengyin Hu a,b,c, Ying Wang a,
Toxicology Letters 2023 Jul; 383:98.
Application:WB, Mouse, C2C12 myoblasts.
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Enhanced myogenesis through lncFAM-mediated recruitment of HNRNPL to the MYBPC2 promoter.
Ming-Wen Chang, Jen-Hao Yang, Dimitrios Tsitsipatis, Xiaoling Yang, Jennifer L Martindale, Rachel Munk, Poonam R Pandey, Nirad Banskota, Brigette Romero, Mona Batish, Yulan Piao, Krystyna Mazan-Mamczarz, Supriyo De, Kotb Abdelmohsen, Gerald M Wilson, Myriam Gorospe.
Nucleic Acids Research 2022 Dec; 50(22):13026.
Application:WB-Ce, Human, AB678 cells.
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Fast and slow skeletal myosin binding protein-C and aging.
L R Perazza, G Wei, L V Thompson.
GeroScience 2023 Apr; 45(2):915.
Application:WB, Mouse, Mouse skeletal muscle.
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Sarcomeric deficits underlie MYBPC1-associated myopathy with myogenic tremor.
Janelle Geist Hauserman, Janis Stavusis, Humberto C Joca, Joel C Robinett, Laurin Hanft, Jack Vandermeulen, Runchen Zhao, Joseph P Stains, Konstantinos Konstantopoulos, Kerry S McDonald, Christopher Ward, Aikaterini Kontrogianni-Konstantopoulos.
JCI Insight 2021 Oct; 6(19):e147612.
Application:WB-Ti, Mouse, Mouse muscles.
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Maternal smoking during pregnancy aggravated muscle phenotype in FHL1 -/y offspring mice similar to congenital clubfoot through P2RX7-mediated pyroptosis.
Yi Lou, Jianing Miao, Fang Li, Jingjing Ding, Lili Wang.
Toxicology Letters 2021 Jul; 345:54.
Application:WB-Ti, Mouse, Mouse lower limbs.
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Trichostatin A inhibits skeletal muscle atrophy induced by cigarette smoke exposure in mice.
Ding J, Li F, Cong Y, Miao J, Wu D, Liu B, Wang L.
Life Sciences 2019 Oct; 235:116800.
Application:IHC-P, WB-Ti, Mouse, Muscle.
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Structure before function: myosin binding protein-C slow is a structural protein with regulatory properties.
Geist J, Ward CW, Kontrogianni-Konstantopoulos A.
FASEB Journal 2018 Jun; fj201800624R.
Application:WB-Ti, Mouse, Mouse muscle.
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Down-regulated Smyd1 participated in the inhibition of myoblast differentiation induced by cigarette smoke extract.
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