PROX1 polyclonal antibody
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More Files
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of PROX1.
Immunogen
A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human PROX1.
Host
Rabbit
Reactivity
Human
Form
Liquid
Purification
Protein G purification
Recommend Usage
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.09% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Transfected lysate)
Western blot analysis of PROX1 (arrow) using PROX1 polyclonal antibody (Cat # PAB1919).
293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the PROX1 gene (Lane 2). -
Gene Info — PROX1
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Interactome
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Disease
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Publication Reference
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The homeobox transcription factor Prox1 inhibits proliferation of hepatocellular carcinoma cells by inducing p53-dependent senescence-like phenotype.
Chang TM, Hung WC.
Cancer Biology & Therapy 2013 Jan; 14(3):222.
Application:WB, IHC, ICC, Human, Mouse, SK-Hep-1, Mouse tumors.
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Mutations and aberrant DNA methylation of the PROX1 gene in hematologic malignancies.
Nagai H, Li Y, Hatano S, Toshihito O, Yuge M, Ito E, Utsumi M, Saito H, Kinoshita T.
Genes, Chromosomes & Cancer 2003 Sep; 38(1):13.
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Prox1 function controls progenitor cell proliferation and horizontal cell genesis in the mammalian retina.
Dyer MA, Livesey FJ, Cepko CL, Oliver G.
Nature Genetics 2003 May; 34(1):53.
Application:IF, IHC-Fr, Mouse, Mouse retinal progenitor cells, Mouse retina.
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Prox1 is a master control gene in the program specifying lymphatic endothelial cell fate.
Hong YK, Harvey N, Noh YH, Schacht V, Hirakawa S, Detmar M, Oliver G.
Developmental Dynamics 2002 Nov; 225(3):351.
Application:IF, IHC-Fr, WB, Human, Mouse, Human dermal microvascular endothelial cells, Mouse skin.
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The homeobox transcription factor Prox1 inhibits proliferation of hepatocellular carcinoma cells by inducing p53-dependent senescence-like phenotype.
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