PRDM16 polyclonal antibody
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
Western Blot (Tissue lysate)
Western blot analysis of rat brain tissue with PRDM16 polyclonal antibody (Cat # PAB19171) at (Lane 1) 1 and (Lane 2) 2 ug/mL dilution.
Immunohistochemistry
Immunohistochemical staining of rat brain tissue with PRDM16 polyclonal antibody (Cat # PAB19171) at 25 ug/mL dilution.
-
Specification
Product Description
Rabbit polyclonal antibody rasied against synthetic peptide of PRDM16.
Immunogen
A synthetic peptide corresponding to 17 amino acids near C-terminus of human PRDM16.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Form
Liquid
Purification
Affinity purification
Concentration
1 mg/mL
Recommend Usage
Western blot (1-2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for up to one year.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Western Blot (Tissue lysate)
Western blot analysis of rat brain tissue with PRDM16 polyclonal antibody (Cat # PAB19171) at (Lane 1) 1 and (Lane 2) 2 ug/mL dilution.Immunohistochemistry
Immunohistochemical staining of rat brain tissue with PRDM16 polyclonal antibody (Cat # PAB19171) at 25 ug/mL dilution.Enzyme-linked Immunoabsorbent Assay
-
Gene Info — PRDM16
Entrez GeneID
63976GeneBank Accession#
CAH71530Gene Name
PRDM16
Gene Alias
KIAA1675, MEL1, MGC166915, PFM13
Gene Description
PR domain containing 16
Omim ID
605557Gene Ontology
HyperlinkGene Summary
The reciprocal translocation t(1;3)(p36;q21) occurs in a subset of myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). This gene is located near the 1p36.3 breakpoint and has been shown to be specifically expressed in the t(1:3)(p36,q21)-positive MDS/AML. The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal PR domain. The translocation results in the overexpression of a truncated version of this protein that lacks the PR domain, which may play an important role in the pathogenesis of MDS and AML. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq
Other Designations
MDS1/EVI1-like|PR-domain zinc finger protein 16|transcription factor MEL1
-
Interactome
-
Disease
-
Publication Reference
-
3,5 Diiodo-l-Thyronine (T₂) Promotes the Browning of White Adipose Tissue in High-Fat Diet-Induced Overweight Male Rats Housed at Thermoneutrality.
Senese R, Cioffi F, De Matteis R, Petito G, de Lange P, Silvestri E, Lombardi A, Moreno M, Goglia F, Lanni A.
Cells 2019 Mar; 8(3):E256.
Application：WB-Ti, Rat, White adipose tissue lysates.
-
RBM4a modulates the impact of PRDM16 on development of brown adipocytes through an alternative splicing mechanism.
Chi YL, Lin JC.
Biochimica et Biophysica Acta. Molecular Cell Research 2018 Nov; 865(11 Pt A):1515.
Application：WB, Mouse, Mouse brown adipocytes.
-
3,5 Diiodo-l-Thyronine (T₂) Promotes the Browning of White Adipose Tissue in High-Fat Diet-Induced Overweight Male Rats Housed at Thermoneutrality.
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com