MRE11A polyclonal antibody
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
Western Blot (Tissue lysate)
Western blot analysis of rat lung tissue with MRE11A polyclonal antibody (Cat # PAB19168) at (Lane 1) 1 and (Lane 2) 2 ug/mL dilution.
Immunohistochemistry
Immunohistochemical staining of rat lung tissue with MRE11A polyclonal antibody (Cat # PAB19168) at 5 ug/mL dilution.
-
Specification
Product Description
Rabbit polyclonal antibody rasied against synthetic peptide of MRE11A.
Immunogen
A synthetic peptide corresponding to 14 amino acids near N-terminus of human MRE11A.
Host
Rabbit
Reactivity
Human, Mouse, Rat
Form
Liquid
Purification
Affinity purification
Concentration
1 mg/mL
Recommend Usage
Western blot (1-2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C for three months. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Applications
Western Blot (Tissue lysate)
Western blot analysis of rat lung tissue with MRE11A polyclonal antibody (Cat # PAB19168) at (Lane 1) 1 and (Lane 2) 2 ug/mL dilution.Immunohistochemistry
Immunohistochemical staining of rat lung tissue with MRE11A polyclonal antibody (Cat # PAB19168) at 5 ug/mL dilution.Enzyme-linked Immunoabsorbent Assay
-
Gene Info — MRE11A
Entrez GeneID
4361GeneBank Accession#
EAW66932Gene Name
MRE11A
Gene Alias
ATLD, HNGS1, MRE11, MRE11B
Gene Description
MRE11 meiotic recombination 11 homolog A (S. cerevisiae)
Gene Ontology
HyperlinkGene Summary
This gene encodes a nuclear protein involved in homologous recombination, telomere length maintenance, and DNA double-strand break repair. By itself, the protein has 3' to 5' exonuclease activity and endonuclease activity. The protein forms a complex with the RAD50 homolog; this complex is required for nonhomologous joining of DNA ends and possesses increased single-stranded DNA endonuclease and 3' to 5' exonuclease activities. In conjunction with a DNA ligase, this protein promotes the joining of noncomplementary ends in vitro using short homologies near the ends of the DNA fragments. This gene has a pseudogene on chromosome 3. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq
Other Designations
AT-like disease|DNA recombination and repair protein|double-strand break repair protein MRE11A|endo/exonuclease Mre11|meiotic recombination 11 homolog A
-
Interactome
-
Pathway
-
Disease
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com