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Last updated: 2016/12/4
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MMP1 polyclonal antibody

  • Catalog # : PAB19141
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against native MMP1.
  • Immunogen:
  • Native purified MMP1 from human synovial fibroblast culture medium.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Specificity:
  • It exhibits moderate cross reactivity with human MMP3 and MMP8.
  • Form:
  • Liquid
  • Purification:
  • Protein A purification
  • Recommend Usage:
  • Western blot (1:300-1:900)
    Immunohistochemistry (1:40-1 :100)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 50 mM Tris-HCl pH 7.4, 100 mM glycine (0.01% thimerosal)
  • Storage Instruction:
  • Store at -80°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains thimerosal: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot
  • Immunohistochemistry
  • Immunofluorescence
  • Immunoprecipitation
  • ELISA
  • Enzyme Immunoassay
  • Flow Cytometry
  • Application Image
  • Western Blot
  • Immunohistochemistry
  • Immunofluorescence
  • Immunoprecipitation
  • ELISA
  • Enzyme Immunoassay
  • Flow Cytometry
  • Gene Information
  • Entrez GeneID:
  • 4312
  • Gene Name:
  • MMP1
  • Gene Alias:
  • CLG,CLGN
  • Gene Description:
  • matrix metallopeptidase 1 (interstitial collagenase)
  • Gene Summary:
  • Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes a secreted enzyme which breaks down the interstitial collagens, types I, II, and III. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. Alternative splicing results in multiple transcript variants.[provided by RefSeq
  • Other Designations:
  • fibroblast collagenase,interstitial collagenase,matrix metalloprotease 1,matrix metalloproteinase 1,matrix metalloproteinase 1 (interstitial collagenase)
  • Interactome
  • Interactome
  • Related Disease
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