CKB polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against full length recombinant CKB.
Immunogen
Recombinant protein corresponding to full length human CKB.
Host
Rabbit
Reactivity
Human
Specificity
It can expression in HEK293 whole cell lysate.
Form
Liquid
Recommend Usage
Western blot (1:500)
The optimal working dilution should be determined by the end user.Storage Buffer
In serum
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot (Cell lysate)
Western blot analysis of HEK293 whole cell lystae with CKB polyclonal antibody (Cat # PAB19125) at 1:500 dilution.Enzyme-linked Immunoabsorbent Assay
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Gene Info — CKB
Entrez GeneID
1152Protein Accession#
P12277Gene Name
CKB
Gene Alias
B-CK, CKBB
Gene Description
creatine kinase, brain
Omim ID
123280Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a cytoplasmic enzyme involved in energy homeostasis. The encoded protein reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in brain as well as in other tissues, and as a heterodimer with a similar muscle isozyme in heart. The encoded protein is a member of the ATP:guanido phosphotransferase protein family. A pseudogene of this gene has been characterized. [provided by RefSeq
Other Designations
brain creatine kinase|creatine kinase B-chain|creatine kinase-B
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Interactome
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Pathway
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Disease
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Publication Reference
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Isoaspartyl Formation in Creatine Kinase B Is Associated with Loss of Enzymatic Activity; Implications for the Linkage of Isoaspartate Accumulation and Neurological Dysfunction in the PIMT Knockout Mouse.
Dimitrijevic A, Qin Z, Aswad DW.
PLoS One 2014 Jun; 9(6):e100622.
Application:WB-Ti, Mouse, Brain.
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Isoaspartyl Formation in Creatine Kinase B Is Associated with Loss of Enzymatic Activity; Implications for the Linkage of Isoaspartate Accumulation and Neurological Dysfunction in the PIMT Knockout Mouse.
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