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Last updated: 2016/12/11

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SOCS2 polyclonal antibody

  • Catalog # : PAB19114
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of SOCS2.
  • Immunogen:
  • A synthetic peptide corresponding to C-terminus of human SOCS2.
  • Host:
  • Rabbit
  • Reactivity:
  • Human, Rat
  • Form:
  • Lyophilized
  • Purification:
  • Immunoaffinity purification
  • Isotype:
  • IgG
  • Recommend Usage:
  • Western Blot (1 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • Lyophilized from 0.9 mg NaCl, 0.2 mg Na2HPO4 (5 mg BSA, 0.05 mg sodium azide, 0.05 mg Thimerosal)
  • Storage Instruction:
  • Store at -20°C on dry atmosphere.
    After reconstitution with 200 uL of deionized water and concentration will be 500 ug/mL, store at -20°C or lower.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide and thimerosal: POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot
  • Western Blot
  • Western blot analysis of tissue and whole cell extracts with SOCS2 polyclonal antibody (Cat # PAB19114).
    Lane 1 : rat brain. Lane 2 : rat liver. Lane 3 : rat spleen. Lane 4 : rat lung.
    Lane 5 : MCF-7. Lane 6 : HeLa. Lane 7 : SMMC. Lane 8 : HT1080.
  • Application Image
  • Gene Information
  • Entrez GeneID:
  • 8835
  • Gene Name:
  • SOCS2
  • Gene Alias:
  • CIS2,Cish2,SOCS-2,SSI-2,SSI2,STATI2
  • Gene Description:
  • suppressor of cytokine signaling 2
  • Gene Summary:
  • This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including erythropoietin, GM-CSF, IL10 and interferon (IFN)-gamma. The protein encoded by this gene is found to interact with the cytoplasmic domain of insulin-like growth factor-1 receptor (IGF1R), and thus is thought to be involved in the regulation of IGF1R mediated cell signaling. Knockout studies in mice also suggested a regulatory role of this gene in IGF-1 related growth control. [provided by RefSeq
  • Other Designations:
  • STAT induced STAT inhibitor-2,cytokine-inducible SH2 protein 2,suppressor of cytokine signaling-2
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