SOCS2 polyclonal antibody
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More Files
- More Functions
Western Blot
Western blot analysis of tissue and whole cell extracts with SOCS2 polyclonal antibody (Cat # PAB19114).
Lane 1 : rat brain. Lane 2 : rat liver. Lane 3 : rat spleen. Lane 4 : rat lung.
Lane 5 : MCF-7. Lane 6 : HeLa. Lane 7 : SMMC. Lane 8 : HT1080.
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of SOCS2.
Immunogen
A synthetic peptide corresponding to C-terminus of human SOCS2.
Host
Rabbit
Reactivity
Human, Rat
Form
Lyophilized
Purification
Immunoaffinity purification
Isotype
IgG
Recommend Usage
Western Blot (1 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
Lyophilized from 0.9 mg NaCl, 0.2 mg Na2HPO4 (5 mg BSA, 0.05 mg sodium azide, 0.05 mg Thimerosal)
Storage Instruction
Store at -20°C on dry atmosphere.
After reconstitution with 200 uL of deionized water and concentration will be 500 ug/mL, store at -20°C or lower.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide and thimerosal: POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western blot analysis of tissue and whole cell extracts with SOCS2 polyclonal antibody (Cat # PAB19114).
Lane 1 : rat brain. Lane 2 : rat liver. Lane 3 : rat spleen. Lane 4 : rat lung.
Lane 5 : MCF-7. Lane 6 : HeLa. Lane 7 : SMMC. Lane 8 : HT1080. -
Gene Info — SOCS2
Entrez GeneID
8835Gene Name
SOCS2
Gene Alias
CIS2, Cish2, SOCS-2, SSI-2, SSI2, STATI2
Gene Description
suppressor of cytokine signaling 2
Omim ID
605117Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including erythropoietin, GM-CSF, IL10 and interferon (IFN)-gamma. The protein encoded by this gene is found to interact with the cytoplasmic domain of insulin-like growth factor-1 receptor (IGF1R), and thus is thought to be involved in the regulation of IGF1R mediated cell signaling. Knockout studies in mice also suggested a regulatory role of this gene in IGF-1 related growth control. [provided by RefSeq
Other Designations
STAT induced STAT inhibitor-2|cytokine-inducible SH2 protein 2|suppressor of cytokine signaling-2
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Interactome
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Pathway
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Disease
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