Rabbit polyclonal antibody raised against synthetic peptide of HSD11B1.
A synthetic peptide corresponding to internal region of human HSD11B1.
Human, Mouse, Rat
Western Blot (1 ug/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1 ug/mL) Immunohistochemistry (Frozen sections) (1 ug/mL) Immunocytochemistry (1 ug/mL) The optimal working dilution should be determined by the end user.
The protein encoded by this gene is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, the encoded protein can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
11-beta-hydroxysteroid dehydrogenase 1,OTTHUMP00000034649,OTTHUMP00000034650,corticosteroid 11-beta-dehydrogenase isozyme 1,short chain dehydrogenase/reductase family 26C, member 1