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Last updated: 2017/1/15
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HLA-DQA2/HLA-DQA1 polyclonal antibody

  • Catalog # : PAB19063
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of HLA-DQA2.
  • Immunogen:
  • A synthetic peptide corresponding to amino acids at C-terminus of human HLA-DQA2.
  • Sequence:
  • C-QGLRSVGASRH
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 28
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 0.5 mg/mL
  • Recommend Usage:
  • ELISA (1:32000)
    Western Blot (1-3 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In Tris saline, pH7.3 (0.5% BSA, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • HLA-DQA2/HLA-DQA1 polyclonal antibody (Cat # PAB19063) (1 ug/mL) staining of human bone marrow lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • ELISA
  • Application Image
  • Western Blot (Tissue lysate)
  • Western Blot (Tissue lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 3118
  • Protein Accession#:
  • NP_064440.1 (Gene ID : 3118);NP_002113.2 (Gene ID : 3117)
  • Gene Name:
  • HLA-DQA2
  • Gene Alias:
  • HLA-DXA
  • Gene Description:
  • major histocompatibility complex, class II, DQ alpha 2
  • Other Designations:
  • OTTHUMP00000029144
  • Gene Information
  • Entrez GeneID:
  • 3117
  • Protein Accession#:
  • NP_064440.1 (Gene ID : 3118);NP_002113.2 (Gene ID : 3117)
  • Gene Name:
  • HLA-DQA1
  • Gene Alias:
  • CD,CELIAC1,DQ-A1,FLJ27088,FLJ27328,GSE,HLA-DQA,MGC149527
  • Gene Description:
  • major histocompatibility complex, class II, DQ alpha 1
  • Gene Summary:
  • HLA-DQA1 belongs to the HLA class II alpha chain paralogues. The class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B Lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa. It is encoded by 5 exons; exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DQ molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to four different molecules. Typing for these polymorphisms is routinely done for bone marrow transplantation. [provided by RefSeq
  • Other Designations:
  • Gluten-sensitive enteropathy (celiac disease),MHC HLA-DQ alpha,MHC class II HLA-D alpha glycoprotein,MHC class II HLA-DQ-alpha-1,MHC class II antigen,MHC class II surface glycoprotein,OTTHUMP00000029141,OTTHUMP00000176885,OTTHUMP00000178551,OTTHUMP0000017
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