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Last updated: 2017/8/13
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ALDH18A1 polyclonal antibody

  • Catalog # : PAB19003
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  • Specification
  • Product Description:
  • Goat polyclonal antibody raised against synthetic peptide of ALDH18A1.
  • Immunogen:
  • A synthetic peptide corresponding to amino acids at C-terminus of humanALDH18A1.
  • Sequence:
  • C-SEHGSLKYLH
  • Host:
  • Goat
  • Theoretical MW (kDa):
  • 85
  • Reactivity:
  • Human
  • Specificity:
  • This antibody is expected to recognize both reported isoforms (NP_002851.2; NP_001017423.1).
  • Form:
  • Liquid
  • Purification:
  • Antigen affinity purification
  • Concentration:
  • 0.5 mg/mL
  • Recommend Usage:
  • ELISA (1:8000)
    Western Blot (1-3 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In 0.5 mg/mL in Tris saline, pH7.3 (0.5% BSA, 0.02% sodium azide)
  • Storage Instruction:
  • Store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • ALDH18A1 polyclonal antibody (Cat # PAB19003, 1 ug/mL) staining of MCF-7 lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • ELISA
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 5832
  • Protein Accession#:
  • NP_002851.2;NP_001017423.1
  • Gene Name:
  • ALDH18A1
  • Gene Alias:
  • GSAS,MGC117316,P5CS,PYCS
  • Gene Description:
  • aldehyde dehydrogenase 18 family, member A1
  • Gene Summary:
  • This gene is a member of the aldehyde dehydrogenase family and encodes a bifunctional ATP- and NADPH-dependent mitochondrial enzyme with both gamma-glutamyl kinase and gamma-glutamyl phosphate reductase activities. The encoded protein catalyzes the reduction of glutamate to delta1-pyrroline-5-carboxylate, a critical step in the de novo biosynthesis of proline, ornithine and arginine. Mutations in this gene lead to hyperammonemia, hypoornithinemia, hypocitrullinemia, hypoargininemia and hypoprolinemia and may be associated with neurodegeneration, cataracts and connective tissue diseases. Alternatively spliced transcript variants, encoding different isoforms, have been described for this gene. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000020159,OTTHUMP00000020160,delta1-pyrroline-5-carboxlate synthetase,glutamate gamma-semialdehyde synthetase,pyrroline-5-carboxlate synthetase,pyrroline-5-carboxylate synthetase,pyrroline-5-carboxylate synthetase (glutamate gamma-semialdehyde sy
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